
Gnotobiotics and the Innovive Research-Ready IVC System
Advancing microbiome research with germ-free rodent housing solutions.
As microbiome research grows, maintaining gnotobiotic rodents in a germ-free setting is crucial. Traditionally, isolators have been the standard, but emerging studies support the use of IVC caging, especially disposable IVC caging, for effective germ-free maintenance.
Why Use a Research-Ready IVC System for Gnotobiotic Research?
Research-Ready cages arrive irradiated, double-bagged, and are guaranteed to have never housed another rodent. This ensures aseptic conditions at the cage level from the very beginning, eliminating the possibility of germs being left behind from the cleaning process. Simply put, you start with a clean, germ-free cage at every change.


Key Benefits of the Research-Ready IVC System for Gnotobiotics

Immediate Usability
Our Research-Ready cages come:
Double-bagged and irradiated
Ready to be used immediately upon arrival, or stored until needed
Options for pre-bedding, pre-filled water bottles, and enrichment
Biosecurity
Our system is engineered for optimal biosecurity, featuring:
Dual HEPA filters at both the rack and cage level (with use of the MVX3 lid)
Racks with adjustable settings for positive and negative airflow
Cage lids that create an airtight seal

This combined approach offers a high level of biocontainment and bioexclusion, ensuring your research remains secure and contamination-free.

"The right caging system will allow you to house gnotobiotic experiments in an outside caging system giving you bioexclusion and biocontainment while using the isolator for its intended purpose of breeding more germ-free mice."
– Stephany Vasquez-Perez | Oregon University
How the Research-Ready System Enhances Your Gnotobiotic Research:
Biocontainment
With advanced airflow and filtration systems, our IVC racks and cages ensure maximum control over environmental conditions.
Aseptic Setup
The irradiated and double-bagged cages ensure that no external contaminants are introduced into your research environment.
Efficiency & Scalability
As your gnotobiotic program expands, the flexible ordering process allows for easy scaling without significant additional investments.