How It Works

High performance IVC Innorack®

• Dual HEPA-filtered ventilation system

• Single and double-sided options, multiple configurations

• Dynamic digital controller

Single-use, recyclable disposable Innocage®

• Variety of caging lids to accommodate all types of research

• Made of 100% high viscosity PET, BPA-free, fully recyclable

• Patented lightweight thin-wall caging

All Innovive disposable caging products are delivered Research-Ready™

Innovive Disposable IVC Rodent Caging System simplifies dirty cage processing:

Simpler Process and Protocols

Disposable Research-Ready™ caging components follow a one-way process flow through the facility and are received directly into clean cage storage¹. The cages arrive sealed in two layers of bagging to ensure biosecurity, and the outer bag can be delayered at any stage based on your facility's flow of operation. When they are ready for use, the inner bag is typically unsealed under a laminar flow hood where cage changes are performed. Standard cage change processes are followed and animals are returned to their ventilated racks (Innorack®). Each cage has the added benefit of never having previously housed another animal.

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With the Innovive Closed-Loop Recycling Service, used disposable cages can be restacked with soiled bedding and sealed back in their original bags. Afterwards, it can be taken straight to the recycling dock of the facility. The Innovive Recycling Service Team then picks up the bags of soiled cages so they can be further processed for recycling and composting.

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¹ In barrier facilities, this can be done effectively by wiping down the double-bagged configuration or stripping off the outer bag as you enter the facility or using a misting tunnel as the point of entry. There is a high degree of flexibility in how direct-to-clean storage is implemented at any facility.

Disposable vs. Traditional Caging

Water Process

Innovive Water Formulation Process

The filling of Aquavive® water bottle occurs within a positive-pressure HEPA-filtered environment. An automated conveyor system fills, caps, dates and labels the bottles. The water is acidified to a range of 2.5 to 3.0 pH before capping. The filled bottles are then packaged in an inner vacuum bag and a secondary containment outer bag for maximum security.

Acidification (pH) Testing

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Acidified water is used to prevent the transfer of bacterial disease between rodents. Our acidification process is carefully managed to add a range of 2.5 to 3.0 pH.

ATP Testing

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We perform tests on water bottles, caps, conveyor belts and filling systems prior to filling to monitor Adenosine Triphosphate (ATP). The luminometer system detects residual ATP as an indicator of surface cleanliness and the possibility of bacterial growth. ATP is measured in Relative Light Units (RLU), and our standard is to provide bottles with less than or equal to 10 RLU.

Point-of-Use Testing

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The point-of-use testing is performed with a filled water bottle that's pulled off the production line. A sample of the water is collected and filtered. The filter is then placed on an agar plate and stored in an incubator to measure any bioburden. Our standard is to produce ultra pure water with less than 0.1 CFU/ml, and less than 500 ppb Total Organic Carbon (TOC). Additionally, we produce chlorinated water with less than 80 ppb of trihalomethanes (THM).

Quality and Testing Standards

Innovive performs consistent water testing to ensure it meets our quality standards before bottles are shipped to facilities. Our water is tested for HPC, TOC (total organic carbon), mold, coliform, and yeast. Customers can trace back to these test results using the date and time stamped on each bottle or the lot number affixed to the pallet.

Recycling with Innocycle